This member of the Cucurbitaceae family was collected by Edward Palmer near Los Angeles Bay in 1887, and described by Sereno Watson in 1889. It can be found in a limited portion of the Sonoran Desert. It preferring a loose sand/grit/gravel mix and some sun, and produces tuberous roots to survive periods of drought. Fruits are approximately eight centimetres, round, and grey-green with lighter stripes. The seeds are ten millimetres long. Some sources list C. cylindrata as a synonym, while other authorities view the two as a case of sympatric speciation.
The genera name from Latin; cucumis; 'gourd'. The species name means 'heart-shaped', referring to leaves. Another wild plant by Jon Rebman, Bajaflora.org.

